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Year : 1991  |  Volume : 23  |  Issue : 4  |  Page : 208--213

Effect of norepinephrine on primary immune response to T-dependent antigen in poultry

S Rishi1, BD Garg2 
1 
2 

Correspondence Address:
S Rishi


1. The effect of in vivo administration of norepinephrine on different days varying from 1 to 8 of immunization on primary humoral immune response to T-dependent antigen in poultry has been studied. 2. Norepinephrine (NE) 1 mg/kg-1 i.v. exhibited an enhancing effect, maximum being on day 4 of immunization.The levels of IgM increased in all the groups up to day 8 whereas levels of IgG increased only when NE was given on days 6,7 or 8 of immunization. 3. The enhancing effect was found to be (-adrenoceptor mediated as it could be blocked by propranolol, a (-adrenoceptor antagonist.The (-adrenoceptor antagonist, phenolamine, failed to block this effect.


How to cite this article:
Rishi S, Garg B D. Effect of norepinephrine on primary immune response to T-dependent antigen in poultry.Indian J Pharmacol 1991;23:208-213


How to cite this URL:
Rishi S, Garg B D. Effect of norepinephrine on primary immune response to T-dependent antigen in poultry. Indian J Pharmacol [serial online] 1991 [cited 2022 Jun 26 ];23:208-213
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1991;volume=23;issue=4;spage=208;epage=213;aulast=Rishi;type=0