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|Year : 1991 | Volume
| Issue : 2 | Page : 81--85
Co-trimoxazole & co-trimazine : A comparative bioavailability study
P Mahajan1, U Tekur2, P Sen3
1. A cross over bioavailability study was carried out with co-ttimoxazole and co-trimazine administered in a dose of 2 tab. BD and 1 tab. BD respectively for 15 doses each, in normal healthy volunteers.
2 Plasma trimethoprim concentration was higher in the co-trimoxazole treated group as compared to the co-trimazine treated group (p<0.02).
3. Serum sulfamethoxazole concentrations were higher than serum sulfadiazine concentrations in the co-trimoxazole and co-trimazine treated groups respectively.
4. The time for reaching the peak and steady state concentrations of drugs in the two treatment groups did not differ significantly for comparable drugs.
|How to cite this article:|
Mahajan P, Tekur U, Sen P. Co-trimoxazole & co-trimazine : A comparative bioavailability study.Indian J Pharmacol 1991;23:81-85
|How to cite this URL:|
Mahajan P, Tekur U, Sen P. Co-trimoxazole & co-trimazine : A comparative bioavailability study. Indian J Pharmacol [serial online] 1991 [cited 2022 Oct 4 ];23:81-85
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1991;volume=23;issue=2;spage=81;epage=85;aulast=Mahajan;type=0