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Year : 1991  |  Volume : 23  |  Issue : 2  |  Page : 117--120

A comparison of “in-vitro” hemolytic effect of some drugs and their interaction with some stabilizers

Roy Dipali1, AB Sarma2 
1 
2 

Correspondence Address:
Roy Dipali


1. In vitro hemolytic effect of phenol and vit A alcohol and its esters were studied on cat, rabbit and human washed RBC suspended in isotonic saline on a comparative basis. 2. Simultaneously, time and temperature dependance study and stabilizing effect of some steroids and (-tocopheryl acetate on drug induced hemolysis were investigated. 3. Vit A alcohol was the most potent hemolytic agent among the vit A preparations. With this drug hemolysis occured even at a low temperature (20ø C). 4. While cholesterol showed no inhibition of drug induced hemolysis, (-tocopheryl acetate was the most effective stabilizer.


How to cite this article:
Dipali R, Sarma A B. A comparison of “in-vitro” hemolytic effect of some drugs and their interaction with some stabilizers.Indian J Pharmacol 1991;23:117-120


How to cite this URL:
Dipali R, Sarma A B. A comparison of “in-vitro” hemolytic effect of some drugs and their interaction with some stabilizers. Indian J Pharmacol [serial online] 1991 [cited 2022 Oct 3 ];23:117-120
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1991;volume=23;issue=2;spage=117;epage=120;aulast=Dipali;type=0