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Year : 1988  |  Volume : 20  |  Issue : 2  |  Page : 90--94

Paracetamol disposition in rat after oral intake of methaqualone

KP Gupta1, KP Bhargava2 
1 
2 

Correspondence Address:
K P Gupta


1. The effect of oral feeding of methaqualone on the pharmacokinetica of paracetamol diapoeition waa studied. 2. Rats given methaqualone (60 mg/kg) orally for a prolonged period were given in addition a single dose of paracetamol (100 mg/kg ip) and pharmacokinetic profile of paracetamol in the plasma and drug levels in liver were estimated. 3.Repeated oral methaqualone intake increased parecetamol disposition.


How to cite this article:
Gupta K P, Bhargava K P. Paracetamol disposition in rat after oral intake of methaqualone.Indian J Pharmacol 1988;20:90-94


How to cite this URL:
Gupta K P, Bhargava K P. Paracetamol disposition in rat after oral intake of methaqualone. Indian J Pharmacol [serial online] 1988 [cited 2021 Sep 25 ];20:90-94
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1988;volume=20;issue=2;spage=90;epage=94;aulast=Gupta;type=0