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Year : 1988  |  Volume : 20  |  Issue : 2  |  Page : 114--121

Effects of cocaine and morphine on vision in rabbits

YK Purandare 
 

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Y K Purandare


1. This study investigated effects of two drugs of abuse. viz. cocaine and morphine on two selected parameters of visual function in rabbits. The e-end-b- wave amplitudes of electroretinogram (ERG), and the wavelength of maximum absorbance (( max.) of the major photosensitive pigment, rhodopsin were studied. 2. There was reduction of a - and b - wave amplitudes under the influence of cocaine. end increase of a - end b-wave amplitudes under the influence of morphine. 3. ER 3 pattern wee distorted by both drugs. 4. High correlation was found between changes of a - end b-wave amplitudes end drug dose levels. 5. ( max. of rhodopsin remained unchanged under the influence of either durg.


How to cite this article:
Purandare Y K. Effects of cocaine and morphine on vision in rabbits.Indian J Pharmacol 1988;20:114-121


How to cite this URL:
Purandare Y K. Effects of cocaine and morphine on vision in rabbits. Indian J Pharmacol [serial online] 1988 [cited 2021 Sep 26 ];20:114-121
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1988;volume=20;issue=2;spage=114;epage=121;aulast=Purandare;type=0