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Year : 1987  |  Volume : 19  |  Issue : 3  |  Page : 186--191

Uptake and release of epinephrine in chicken liver: in vitro studies

AK Aggarwal1, S Rishi2, BD Garg3 
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Correspondence Address:
A K Aggarwal


1. The epinephrine (E) content in white leg horn ( WLH ) chicken liver was estimated to be three-times less then norepinephrine (NE). 2. The liver slices were able to accumulate high concentration of E from the incubation media and this was found to be a concentration and time dependent phenomenon with peak accumulation occuring after 45 min. of incubation at 10-4M concentration of the amine. This process could be significantly blocked by cocaine, metanephrine and phenoxybenzamine. Following maximum accumulation, the amine showed linear disappearance when incubated in amine free media. 3. In tissue slices taken from reserpine treated group, the rate constant of disappearance (K) was much faster, decreasing its half life, as compared to control.


How to cite this article:
Aggarwal A K, Rishi S, Garg B D. Uptake and release of epinephrine in chicken liver: in vitro studies.Indian J Pharmacol 1987;19:186-191


How to cite this URL:
Aggarwal A K, Rishi S, Garg B D. Uptake and release of epinephrine in chicken liver: in vitro studies. Indian J Pharmacol [serial online] 1987 [cited 2021 Sep 25 ];19:186-191
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1987;volume=19;issue=3;spage=186;epage=191;aulast=Aggarwal;type=0