Indian Journal of Pharmacology Home 

SHORT COMMUNICATION
[Download PDF]
Year : 1986  |  Volume : 18  |  Issue : 2  |  Page : 100--101

Effect of debrisoquine oxidation status on ethinylestradiol pharmacokinetics in normal healthy female volunteers

NA Kshirsagar1, PM Nadkarni2, GM Sankolli3, UM Joshi4, RS Satoskar5 
1 
2 
3 
4 
5 

Correspondence Address:
N A Kshirsagar


1. Plasma levels of ethinylestradiol (EE) were studied in normal healthy females, who were either fast, intermediate or slow oxidizers of debrisoquine. 2. No statistically significant correlation was found between Area Under Curve (AUC) and maximum levels (CMax) of EE in different oxidation phenotypes. 3. It is concluded that slow oxidizers are not at greater risk of concentration-dependent toxicity of EE.


How to cite this article:
Kshirsagar N A, Nadkarni P M, Sankolli G M, Joshi U M, Satoskar R S. Effect of debrisoquine oxidation status on ethinylestradiol pharmacokinetics in normal healthy female volunteers.Indian J Pharmacol 1986;18:100-101


How to cite this URL:
Kshirsagar N A, Nadkarni P M, Sankolli G M, Joshi U M, Satoskar R S. Effect of debrisoquine oxidation status on ethinylestradiol pharmacokinetics in normal healthy female volunteers. Indian J Pharmacol [serial online] 1986 [cited 2022 Jan 20 ];18:100-101
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1986;volume=18;issue=2;spage=100;epage=101;aulast=Kshirsagar;type=0