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| Year : 1986 | Volume
: 18
| Issue : 2 | Page : 100--101 |
Effect of debrisoquine oxidation status on ethinylestradiol pharmacokinetics in normal healthy female volunteers
NA Kshirsagar1, PM Nadkarni2, GM Sankolli3, UM Joshi4, RS Satoskar5
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Correspondence Address:
N A Kshirsagar
1. Plasma levels of ethinylestradiol (EE) were studied in normal healthy females, who were either fast, intermediate or slow oxidizers of debrisoquine.
2. No statistically significant correlation was found between Area Under Curve (AUC) and maximum levels (CMax) of EE in different oxidation phenotypes.
3. It is concluded that slow oxidizers are not at greater risk of concentration-dependent toxicity of EE.
How to cite this article:
Kshirsagar N A, Nadkarni P M, Sankolli G M, Joshi U M, Satoskar R S. Effect of debrisoquine oxidation status on ethinylestradiol pharmacokinetics in normal healthy female volunteers.Indian J Pharmacol 1986;18:100-101
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How to cite this URL:
Kshirsagar N A, Nadkarni P M, Sankolli G M, Joshi U M, Satoskar R S. Effect of debrisoquine oxidation status on ethinylestradiol pharmacokinetics in normal healthy female volunteers. Indian J Pharmacol [serial online] 1986 [cited 2023 Jun 10 ];18:100-101
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1986;volume=18;issue=2;spage=100;epage=101;aulast=Kshirsagar;type=0 |
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