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Year : 1985  |  Volume : 17  |  Issue : 3  |  Page : 155--157

Local anaesthetic activity of some parasubstituted acetophenone mannich bases

SC Chaturvedi1, GK Patnaik2, BN Dhawan3, VK Dixit4 
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Correspondence Address:
S C Chaturvedi


1. Twenty five Mannich bases of para substituted acetophenones were synthesized and tested for local anaesthetic activity in rabbits and guineapigs. 2 All the compounds of dibenzyl series showed significant surface and infiltration anaesthetic activity. 3. In the piperidine series only compound (-piperidinoethyl p-chlorophenyl ketone HCI showed local anaesthetic activity. This compound did not possess any local irritant effect.


How to cite this article:
Chaturvedi S C, Patnaik G K, Dhawan B N, Dixit V K. Local anaesthetic activity of some parasubstituted acetophenone mannich bases.Indian J Pharmacol 1985;17:155-157


How to cite this URL:
Chaturvedi S C, Patnaik G K, Dhawan B N, Dixit V K. Local anaesthetic activity of some parasubstituted acetophenone mannich bases. Indian J Pharmacol [serial online] 1985 [cited 2022 Aug 8 ];17:155-157
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1985;volume=17;issue=3;spage=155;epage=157;aulast=Chaturvedi;type=0