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Year : 1984  |  Volume : 16  |  Issue : 4  |  Page : 225--227

Pharmacokinetics of dapsone in presence of dipyrone in leprosy patients

DR Krishna1, Rao AVN Appa2, TV Ramanakar3, MC Prabhakar4 
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Correspondence Address:
D R Krishna


1 Different pharmacokinetic parameters of dapsone were studied, following oral administration of dapsone (100 mg.) alone or in combination with dipyrone(1000 mg.) in six untreated patients of leprosy, over a period of 8 hours. 2. The mean blood levels, the mean serum half-life and the mean AUC O-8 hrs of dapsone were reduced in the presence of dipyrone. 3. The cumulative urinary excretion of dapsone was increased following the administration of dapsone and dipyrone in combination.


How to cite this article:
Krishna D R, Appa RA, Ramanakar T V, Prabhakar M C. Pharmacokinetics of dapsone in presence of dipyrone in leprosy patients.Indian J Pharmacol 1984;16:225-227


How to cite this URL:
Krishna D R, Appa RA, Ramanakar T V, Prabhakar M C. Pharmacokinetics of dapsone in presence of dipyrone in leprosy patients. Indian J Pharmacol [serial online] 1984 [cited 2021 Dec 5 ];16:225-227
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1984;volume=16;issue=4;spage=225;epage=227;aulast=Krishna;type=0