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Year : 1984  |  Volume : 16  |  Issue : 2  |  Page : 99--101

Activities of glucose 6 phosphate and sorbitol dehydrogenases in alloxan induced cataract: an experimental study

UM Rawal1, DN Gandhi2 
1 
2 

Correspondence Address:
U M Rawal


1. Decrease in the activity of glucose 6 phosphate dehydrogenase (G6PDH), sorbitol dehydrogenase (SDH) and NADP has been suggested as a possible cause of cataract formation, via the effects on glycolysis, HMP shunt and sorbitol pathways in galactosemic and other types of cataract 2. In contrast to normal lenses alloxan-induced cataractous lenses showed a decrease in the activities of G 6 PDH and SDH in blood, aqueous humor and lens. 3. The results indicate that aloxan-induced cataract has an inhibitory effect on some of the lenticubr metabolic pathways.


How to cite this article:
Rawal U M, Gandhi D N. Activities of glucose 6 phosphate and sorbitol dehydrogenases in alloxan induced cataract: an experimental study.Indian J Pharmacol 1984;16:99-101


How to cite this URL:
Rawal U M, Gandhi D N. Activities of glucose 6 phosphate and sorbitol dehydrogenases in alloxan induced cataract: an experimental study. Indian J Pharmacol [serial online] 1984 [cited 2022 Aug 17 ];16:99-101
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1984;volume=16;issue=2;spage=99;epage=101;aulast=Rawal;type=0