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Year : 1980  |  Volume : 12  |  Issue : 2  |  Page : 85--91

Sphaeroides oblongus: cardiovascular and respiratory effects

Sanyal Bratati1, BB Patra2, BP Mukherjee3, S Ganguli4 
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Correspondence Address:
Sanyal Bratati


. A toxic principle (FT) isolated from Sphaeroides oblongus, a poisonous fish, showed dose-dependent (25-800 ęg/kg) decreasein cardiac rate and blood pressure accompanied by respiratory depression including transient apnoeic phases in urethane-anaesthetized cat preparations. A peripheral mechanism of action comprising blockade of sympathetic (vasomotor) axonal conductiion, a transient myocardial depression and partial direct musculotropic effect is suggested to be responsible for the bradycardia, hypotension and respiratory depression.


How to cite this article:
Bratati S, Patra B B, Mukherjee B P, Ganguli S. Sphaeroides oblongus: cardiovascular and respiratory effects.Indian J Pharmacol 1980;12:85-91


How to cite this URL:
Bratati S, Patra B B, Mukherjee B P, Ganguli S. Sphaeroides oblongus: cardiovascular and respiratory effects. Indian J Pharmacol [serial online] 1980 [cited 2021 Apr 19 ];12:85-91
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1980;volume=12;issue=2;spage=85;epage=91;aulast=Bratati;type=0