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Year : 1980  |  Volume : 12  |  Issue : 2  |  Page : 123--127

Pancreatic beta cell regeneration a novel antidiabetic mechanism of Pterocarpus marsupium roxb

BK Chakravarthy1, Gupta Saroj2, SS Gambhir3, KD Gode4 
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Correspondence Address:
B K Chakravarthy


. A flavonoid fraction (XE) extracted from the bark of pterocarpus marsupium Roxb. (Leguminoceae) was studied for the hypoglycaemic activity normal and alloxanised albino rats. The drug XE did not show a consistent effect on normal blood sugar levels but it effectively reversed the alloxan-induced changes in the blood sugar level and the beta-cell population in the pancreas. It also showed a protective effect when it was given prior to alloxan administration. The novel action of drug on the pancreatic beta-cells and absence of acute toxicity may offer a new hope to the diabetics in future.


How to cite this article:
Chakravarthy B K, Saroj G, Gambhir S S, Gode K D. Pancreatic beta cell regeneration a novel antidiabetic mechanism of Pterocarpus marsupium roxb.Indian J Pharmacol 1980;12:123-127


How to cite this URL:
Chakravarthy B K, Saroj G, Gambhir S S, Gode K D. Pancreatic beta cell regeneration a novel antidiabetic mechanism of Pterocarpus marsupium roxb. Indian J Pharmacol [serial online] 1980 [cited 2022 Jul 1 ];12:123-127
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1980;volume=12;issue=2;spage=123;epage=127;aulast=Chakravarthy;type=0