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Year : 1979  |  Volume : 11  |  Issue : 4  |  Page : 273--276

Bioavailability of oleandomycin: A comparison of the phosphate and triacetyl esters

AS Nanivadekar 
 

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A S Nanivadekar


. In a randomised crossover study on 20 human volunteers, oleandomycin phosphate and triacetyl oleandomycin produced comparable mean serum levels following an oral dose equivalent to 500 mg oleandomycin.The triacetyl ester produced significantly lower level in 4 of the subjects, which could be due to inadequate hydrolysis of the ester in the gut on account of poor esterase activity.


How to cite this article:
Nanivadekar A S. Bioavailability of oleandomycin: A comparison of the phosphate and triacetyl esters.Indian J Pharmacol 1979;11:273-276


How to cite this URL:
Nanivadekar A S. Bioavailability of oleandomycin: A comparison of the phosphate and triacetyl esters. Indian J Pharmacol [serial online] 1979 [cited 2022 Nov 30 ];11:273-276
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1979;volume=11;issue=4;spage=273;epage=276;aulast=Nanivadekar;type=0