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Year : 1977  |  Volume : 9  |  Issue : 4  |  Page : 305--309

Synthesis and pharmacology of 5-(NN-(Dialkylamino)-acetamido)-3,4-dimethyl isoxazoles

JP Trivedi1, TP Gandhi2, VC Patel3 
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Correspondence Address:
J P Trivedi


Eight isoxazoles (1 to 8) were synthesised in our laboratory. Five compounds (1 to 5) were selected for pharmacological screening. All the compounds showed local anaesthetic, spasmolytic and anti-epileptic activity. Dibenzylamino derivative was found to be most potent. less irritant and less toxic compound comparable to lignocaine.


How to cite this article:
Trivedi J P, Gandhi T P, Patel V C. Synthesis and pharmacology of 5-(NN-(Dialkylamino)-acetamido)-3,4-dimethyl isoxazoles.Indian J Pharmacol 1977;9:305-309


How to cite this URL:
Trivedi J P, Gandhi T P, Patel V C. Synthesis and pharmacology of 5-(NN-(Dialkylamino)-acetamido)-3,4-dimethyl isoxazoles. Indian J Pharmacol [serial online] 1977 [cited 2022 Oct 2 ];9:305-309
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=4;spage=305;epage=309;aulast=Trivedi;type=0