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Year : 1977  |  Volume : 9  |  Issue : 4  |  Page : 301--304

A possible involvement of presynaptic receptors in action of apomorphine and clonidine in open field situation

PC Dandiya1, RC Chowdhri2, OP Mangal3 
1 
2 
3 

Correspondence Address:
P C Dandiya


Both clonidine and apomorphine lowered the open field performance of albino rats. Both when given individually along with antiparkinsonian agents like I-DOPA. benztropine and d -amphetamine lowered the open field scores of these antiparkinsonian agents. The parallel effects of apomorphine and clonidine suggest a common mechanism for their action i.e. stimulation of prarynaptic dopamine and/or norepinephrine receptors in CNS which regulate synthesis and release of DA and/or NE.


How to cite this article:
Dandiya P C, Chowdhri R C, Mangal O P. A possible involvement of presynaptic receptors in action of apomorphine and clonidine in open field situation.Indian J Pharmacol 1977;9:301-304


How to cite this URL:
Dandiya P C, Chowdhri R C, Mangal O P. A possible involvement of presynaptic receptors in action of apomorphine and clonidine in open field situation. Indian J Pharmacol [serial online] 1977 [cited 2022 Oct 4 ];9:301-304
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=4;spage=301;epage=304;aulast=Dandiya;type=0