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Year : 1977  |  Volume : 9  |  Issue : 4  |  Page : 285--289

Hyperglycaemic effect of angiotensin

KN Singh1, S Agarwal2, V Chandra3 
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2 
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Correspondence Address:
K N Singh


Intracerebroventricular administration of angiotensin (10 (g) caused a rise in blood glucose level in rabbits. The hyperglycaemia was not affected by bilateral vagotomy and was less marked in adrenalectomized rabbits. The hyperglycaemic effect was not observed in reserpinized and spinal vagotomized rabbits. It is suggested that intracerebroventricular administration of angiotensin stimulates the hypothalamic or medullary accelerator neurons (central sympathetic structures) to cause a marked release of catecholamines from peripheral stores specially adrenal medulla. This excessive release of catecholamines is responsible for hyperglyoaemia induced by angiotensin-II in rabbits.


How to cite this article:
Singh K N, Agarwal S, Chandra V. Hyperglycaemic effect of angiotensin.Indian J Pharmacol 1977;9:285-289


How to cite this URL:
Singh K N, Agarwal S, Chandra V. Hyperglycaemic effect of angiotensin. Indian J Pharmacol [serial online] 1977 [cited 2022 Oct 4 ];9:285-289
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=4;spage=285;epage=289;aulast=Singh;type=0