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Year : 1977  |  Volume : 9  |  Issue : 4  |  Page : 273--277

Cardiovascular and other pharmacological actions of ketamine

Rao P Prabhakar1, VSV Subbu2 
1 
2 

Correspondence Address:
Rao P Prabhakar


Cardiovascular effects of ketamine (KT) were studied in dogs in varying doses upto 20 mg/kg body weight. KT when administered intravenously in small doses produced a transient rise in blood pressure and subsequently a fall in blood pressure was observed with a dose of 10 mg/kg and above, The transient rise in blood pressure might be due to the release of catecholamines. KT is a relaxant to the plain muscle, mainly intestines and peripheral vasculature. It is a mild analgesic agent when compared to pethidine and morphine. KT raises the body temperature in rabbits by about 1 C.


How to cite this article:
Prabhakar RP, Subbu V. Cardiovascular and other pharmacological actions of ketamine.Indian J Pharmacol 1977;9:273-277


How to cite this URL:
Prabhakar RP, Subbu V. Cardiovascular and other pharmacological actions of ketamine. Indian J Pharmacol [serial online] 1977 [cited 2022 Oct 3 ];9:273-277
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=4;spage=273;epage=277;aulast=Prabhakar;type=0