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Year : 1977  |  Volume : 9  |  Issue : 4  |  Page : 259--264

Phenothiazines as histamine and serotonin antagonists without sedation: Part II

Singh Vijai1, HL Sharma2, VN Sharma3 
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2 
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Correspondence Address:
Singh Vijai


A series of 10-N-acylamino phenothaizines posse-sing N-(-hydroxyethyl piperazine moiety in their side chain showed antihistaminic, antispasmodic and antiserotoninergic activity. On comparison with promethazine HCI, diphenhydramine HCI and cyproheptadine HCI, the compounds of this series were found feeble in potency but less toxic. All the test compounds were devoid of central nervous system depressant activity.


How to cite this article:
Vijai S, Sharma H L, Sharma V N. Phenothiazines as histamine and serotonin antagonists without sedation: Part II.Indian J Pharmacol 1977;9:259-264


How to cite this URL:
Vijai S, Sharma H L, Sharma V N. Phenothiazines as histamine and serotonin antagonists without sedation: Part II. Indian J Pharmacol [serial online] 1977 [cited 2022 Oct 4 ];9:259-264
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=4;spage=259;epage=264;aulast=Vijai;type=0