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Neuroprotectant Effects of Hibiscetin in 3-Nitropropionic Acid-Induced Huntington’s Disease via Subsiding Oxidative Stress and Modulating Monoamine Neurotransmitters in Rats Brain |
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| Wael A. Mahdi, Shareefa A. AlGhamdi, Amira M. Alghamdi, Syed Sarim Imam, Sultan Alshehri, Mohammad A. Almaniea, Baraa Mohammed Hajjar, Fahad A. Al-Abbasi, Nadeem Sayyed, Imran Kazmi |
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Activating SIRT-1 Signalling with the Mitochondrial-CoQ10 Activator Solanesol Improves Neurobehavioral and Neurochemical Defects in Ouabain-Induced Experimental Model of Bipolar Disorder |
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| Bidisha Rajkhowa, Sidharth Mehan, Pranshul Sethi, Aradhana Prajapati, Manisha Suri, Sumit Kumar, Sonalika Bhalla, Acharan S. Narula, Abdulrahman Alshammari, Metab Alharbi, Nora Alkahtani, Saeed Alghamdi, Reni Kalfin |
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Protective effects of apigenin on methylmercury-induced behavioral/neurochemical abnormalities and neurotoxicity in rats |
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| Rajeshwar Kumar Yadav, Sidharth Mehan, Rakesh Sahu, Sumit Kumar, Andleeb Khan, Hafiz Antar Makeen, Mohammed Al Bratty |
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| Human & Experimental Toxicology. 2022; 41: 0960327122 |
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Butin Attenuates Arthritis in Complete Freund’s Adjuvant-Treated Arthritic Rats: Possibly Mediated by Its Antioxidant and Anti-Inflammatory Actions |
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| Sami I. Alzarea, Abdullah F. Alasmari, Abdullah S. Alanazi, Abdulaziz I. Alzarea, Metab Alharbi, Abdulrahman Alshammari, Imran Kazmi, Fakhria A. Aljoufi, Nadeem Sayyed, Muhammad Afzal |
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Anti-Huntington’s Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents |
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| Muhammad Afzal, Nadeem Sayyed, Khalid Saad Alharbi, Sami I. Alzarea, Mohammed Salem Alshammari, Fadhel A. Alomar, Sattam Khulaif Alenezi, Anwarulabedin Mohsin Quazi, Abdulaziz I. Alzarea, Imran Kazmi |
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Protective Effect of Fustin against Huntington’s Disease in 3-Nitropropionic Treated Rats via Downregulation of Oxidative Stress and Alteration in Neurotransmitters and Brain-Derived Neurotrophic Factor Activity |
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| May Nasser Bin-Jumah, Sadaf Jamal Gilani, Abdulaziz F. Alabbasi, Fahad A. Al-Abbasi, Shareefa A. AlGhamdi, Ohoud Y. Alshehri, Amira M. Alghamdi, Nadeem Sayyed, Imran Kazmi |
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Smo-Shh Agonist Purmorphamine Prevents Neurobehavioral and Neurochemical Defects in 8-OH-DPAT-Induced Experimental Model of Obsessive-Compulsive Disorder |
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| Ria Gupta, Sidharth Mehan, Pranshul Sethi, Aradhana Prajapati, Abdulrahman Alshammari, Metab Alharbi, Haneen A. Al-Mazroua, Acharan S. Narula |
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| Brain Sciences. 2022; 12(3): 342 |
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Nrf2/HO-1 Signaling Stimulation through Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) Provides Neuroprotection in Ethidium Bromide-Induced Experimental Model of Multiple Sclerosis |
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| Shubham Upadhayay, Sidharth Mehan, Aradhana Prajapati, Pranshul Sethi, Manisha Suri, Ayat Zawawi, Majed N. Almashjary, Shams Tabrez |
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| Genes. 2022; 13(8): 1324 |
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Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism |
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| Rishabh Khera, Sidharth Mehan, Sonalika Bhalla, Sumit Kumar, Abdulrahman Alshammari, Metab Alharbi, Satya Sai Sadhu |
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| Molecules. 2022; 27(3): 889 |
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Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity |
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| Ambika Shandilya, Sidharth Mehan, Sumit Kumar, Pranshul Sethi, Acharan S. Narula, Abdulrahman Alshammari, Metab Alharbi, Abdullah F. Alasmari |
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| Molecules. 2022; 27(12): 3878 |
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PI3K/AKT/mTOR signalling inhibitor chrysophanol ameliorates neurobehavioural and neurochemical defects in propionic acid-induced experimental model of autism in adult rats |
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| Aarti Sharma, Sonalika Bhalla, Sidharth Mehan |
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Neuroprotective Effect of Chrysophanol as a PI3K/AKT/mTOR Signaling Inhibitor in an Experimental Model of Autologous Blood-induced Intracerebral Hemorrhage |
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| Kuldeep Singh Jadaun, Sidharth Mehan, Aarti Sharma, Ehraz Mehmood Siddiqui, Sumit Kumar, Naif Alsuhaymi |
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Neuroprotective Effect of Chrysophanol as a PI3K/AKT/mTOR Signaling Inhibitor in an Experimental Model of Autologous Blood-induced Intracerebral Hemorrhage |
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| Kuldeep Singh Jadaun, Sidharth Mehan, Aarti Sharma, Ehraz Mehmood Siddiqui, Sumit Kumar, Naif Alsuhaymi |
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Anti-Huntington’s Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action |
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| Sultan Alshehri, Fahad A. Al-Abbasi, Mohammed M. Ghoneim, Syed Sarim Imam, Muhammad Afzal, Khalid Saad Alharbi, Muhammad Shahid Nadeem, Nadeem Sayyed, Imran Kazmi |
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4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in experimental rats |
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| Sonalika Bhalla, Sidharth Mehan |
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Effect of alpha-mangostin in the prevention of behavioral and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats |
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| Rakesh Sahu, Sidharth Mehan, Sumit Kumar, Aradhana Prajapati, Abdulrahman Alshammari, Metab Alharbi, Mohammed A. Assiri, Acharan S Narula |
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Protective Effect of Natural Products against Huntington’s Disease: An Overview of Scientific Evidence and Understanding Their Mechanism of Action |
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| Pei Teng Lum, Mahendran Sekar, Siew Hua Gan, Srinivasa Reddy Bonam, Mohd. Farooq Shaikh |
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Everolimus: A potential therapeutic agent targeting PI3K/Akt pathway in brain insulin system dysfunction and associated neurobehavioral deficits |
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| Seema Bansal, Madhunika Agrawal, Saniya Mahendiratta, Subodh Kumar, Shiyana Arora, Rupa Joshi, Manisha Prajapat, Phulen Sarma, Ajay Prakash, Kanwaljit Chopra, Bikash Medhi |
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| Fundamental & Clinical Pharmacology. 2021; 35(6): 1018 |
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Smo-Shh signaling activator purmorphamine ameliorates neurobehavioral, molecular, and morphological alterations in an intracerebroventricular propionic acid-induced experimental model of autism |
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| S Rahi, R Gupta, A Sharma, S Mehan |
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| Human & Experimental Toxicology. 2021; 40(11): 1880 |
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| 20 |
Neuroprotection by solanesol against ethidium bromide-induced multiple sclerosis-like neurobehavioral, molecular, and neurochemical alterations in experimental rats |
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| Nidhi Sharma, Shubham Upadhayay, Ambika Shandilya, Rakesh Sahu, Anshuman Singh, Bidisha Rajkhowa, Sidharth Mehan |
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| 21 |
Inhibition of c-JNK/p38MAPK signaling pathway by Apigenin prevents neurobehavioral and neurochemical defects in ethidium bromide-induced experimental model of multiple sclerosis in rats: Evidence from CSF, blood plasma and brain samples |
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| Anshuman Singh, Shubham Upadhayay, Sidharth Mehan |
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| Phytomedicine Plus. 2021; 1(4): 100139 |
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Neuroprotective efficacy of 4-Hydroxyisoleucine in experimentally induced intracerebral hemorrhage |
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| Ehraz Mehmood Siddiqui, Sidharth Mehan, Shubham Upadhayay, Andleeb Khan, Maryam Halawi, Azhar Ahmed Halawi, Rana M. Alsaffar |
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| Saudi Journal of Biological Sciences. 2021; 28(11): 6417 |
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Nrf2/HO-1 Signaling Activator Acetyl-11-keto-beta Boswellic Acid (AKBA)-Mediated Neuroprotection in Methyl Mercury-Induced Experimental Model of ALS |
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| Elizabeth Minj, Shubham Upadhayay, Sidharth Mehan |
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| Neurochemical Research. 2021; 46(11): 2867 |
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Metformin ameliorates the status epilepticus- induced hippocampal pathology through possible mTOR modulation |
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| Sree Lalitha Bojja, Bikash Medhi, Shashi Anand, Alka Bhatia, Rupa Joshi, Ranjana W. Minz |
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| Inflammopharmacology. 2021; 29(1): 137 |
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Guggulsterone ameliorates ethidium bromide-induced experimental model of multiple sclerosis via restoration of behavioral, molecular, neurochemical and morphological alterations in rat brain |
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| Nitish Kumar, Nidhi Sharma, Rishabh Khera, Ria Gupta, Sidharth Mehan |
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Neuroprotective Effect of a-Mangostin in Ameliorating Propionic Acid-Induced Experimental Model of Autism in Wistar Rats |
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| Aarti Tiwari, Rishabh Khera, Saloni Rahi, Sidharth Mehan, Hafiz Antar Makeen, Yahya H. Khormi, Muneeb U Rehman, Andleeb Khan |
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| Brain Sciences. 2021; 11(3): 288 |
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Current Neuropharmacological Interventions in Autism: Potential Drug Targets from Pre-clinical and Clinical Findings |
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| Ramit Sharma, Aarti Tiwari, Saloni Rahi, Sidharth Mehan |
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Exploring Molecular Approaches in Amyotrophic Lateral Sclerosis: Drug Targets from Clinical and Pre-Clinical Findings |
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| Mamtaj Alam, Rajeshwar K. Yadav, Elizabeth Minj, Aarti Tiwari, Sidharth Mehan |
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Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats |
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| Flavia Tasmin Techera Antunes, Alessandra Hubner de Souza, Emanuelle Sistherenn Caminski, Samuel Greggio, Gianina Teribele Venturin, Jaderson Costa da Costa, Maitê Taffarel, Isadora Nunes Rebelo, Marcus Vinicius Gomez, Dione Silva Correa, Fernanda Nunes Vilanova, Andrea Pereira Regner, Eliane Dallegrave |
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Neuroprotective potential of solanesol in a combined model of intracerebral and intraventricular hemorrhage in rats |
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| Kajal Rajdev, Ehraz Mehmood Siddiqui, Kuldeep Singh Jadaun, Sidharth Mehan |
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