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Year : 2023  |  Volume : 55  |  Issue : 2  |  Page : 138-140

Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature

1 Department of Dermatology, Military Hospital Agra, Agra, Uttar Pradesh, India
2 Department of Internal Medicine, Military Hospital Agra, Agra, Uttar Pradesh, India

Correspondence Address:
Sushil Kumar
MLN Medical College, Prayagraj, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijp.ijp_811_21

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All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications. We describe two cases who developed genital ulcers while treated with ATRA.


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