| DRUG WATCH |
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| Year : 2023 | Volume
: 55
| Issue : 2 | Page : 138-140 |
Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature
Neerja Saraswat1, Sushil Kumar1, Rahul Prem2, Durga Madhab Tripathi1
1 Department of Dermatology, Military Hospital Agra, Agra, Uttar Pradesh, India
2 Department of Internal Medicine, Military Hospital Agra, Agra, Uttar Pradesh, India
Correspondence Address:
Sushil Kumar
MLN Medical College, Prayagraj, Uttar Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijp.ijp_811_21
All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications. We describe two cases who developed genital ulcers while treated with ATRA.
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