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| RESEARCH ARTICLE
|Year : 2022 | Volume
| Issue : 5 | Page : 321-328
Assessment of prescribing pattern of drugs and completeness of prescriptions as per the World Health Organization prescribing indicators in various Indian tertiary care centers: A multicentric study by Rational Use of Medicines Centers-Indian Council of Medical Research network under National Virtual Centre Clinical Pharmacology activity
R Joshi1, B Medhi1, A Prakash1, S Chandy2, J Ranjalkar2, HR Bright2, J Basker2, L Govindraj2, PK Chugh3, CD Tripathi3, DK Badyal4, S Balakrishnan5, R Jhaj5, AK Shukla5, S Atal5, A Najmi5, A Banerjee5, S Kamat6, RK Tripathi6, YC Shetty6, U Parmar6, N Rege6, H Dikshit7, H Mishra7, SS Roy7, S Chatterjee8, A Hazra8, M Bhattacharya8, D Das8, N Trivedi9, P Shah9, J Chauhan9, C Desai10, AM Gandhi10, PP Patel10, S Shah10, S Sheth10, R Raveendran11, J Mathaiyan11, S Manikandan11, G Jeevitha11, P Gupta12, SC Sarangi12, HN Yadav12, S Singh12, S Kaushal13, S Arora13, K Gupta13, S Jain13, JJ Cherian14, NS Chatterjee14, R Kaul14, NA Kshirsagar14
1 Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India
3 Vardhman Mahavir Medical College, New Delhi, India
4 Department of Pharmacology, Christian Medical College, Ludhiana, Punjab, India
5 Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India
6 Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India
7 Department of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
8 Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
9 Department of Pharmacology, Government Medical College, Baroda, Gujarat, India
10 Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India
11 Department of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India
12 Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
13 Department of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India
14 Indian Council of Medical Research, New Delhi, India
OBJECTIVE: The rational use of medicines as per the World Health Organization (WHO) should be practiced globally. However, data regarding the completeness of the prescriptions and their rational use is lacking from developing countries like India. Thus, the aim of this study was to assess the prescribing patterns of drugs and completeness of prescriptions as per WHO core drug use and complementary indicators to provide real-life examples for the Indian Council of Medical Research (ICMR) online prescribing skill course for medical graduates.
METHODS: Prescriptions of the patients, fulfilling inclusion criteria, attending Outpatient Departments of various specialties of tertiary care hospitals, were collected by thirteen ICMR Rational use of medicines centers located in tertiary care hospitals, throughout India. Prescriptions were evaluated for rational use of medicines according to the WHO guidelines and for appropriateness as per standard treatment guidelines using a common protocol approved by local Ethics committees.
RESULTS: Among 4838 prescriptions, an average of about three drugs (3.34) was prescribed to the patients per prescription. Polypharmacy was noted in 83.05% of prescriptions. Generic drugs were prescribed in 47.58% of the prescriptions. Further, antimicrobials were prescribed in 17.63% of the prescriptions and only 4.98% of prescriptions were with injectables. During the prescription evaluation, 38.65% of the prescriptions were incomplete due to multiple omissions such as dose, duration, and formulation.
CONCLUSION: Most of the parameters in the present study were out of the range of WHO-recommended prescribing indicators. Therefore, effective intervention program, like training, for the promotion of rational drug use practice was recommended to improve the prescribing pattern of drugs and the quality of prescriptions all over the country.
Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh
Source of Support: None, Conflict of Interest: None
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