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Year : 2022  |  Volume : 54  |  Issue : 2  |  Page : 138-145

Animal models - Mimicking the pain of trigeminal neuralgia


1 Department of Clinical Research, Dasmesh Institute of Research and Dental Sciences, Faridkot Punjab, India
2 Department of Hospital Administration, Guru Gobind Singh Medical Hospital, Faridkot Punjab, India
3 Department of Oral & Maxillofacial Surgery, Dasmesh Institute of Research and Dental Sciences, Faridkot Punjab, India

Correspondence Address:
Dr. Ravinder Nath Bansal
Hospital Administration, Guru Gobind Singh Medical Hospital, Faridkot, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijp.ijp_296_19

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Trigeminal neuralgia (TN) is an episodic facial pain which feels like an electric shock of unilateral origin. This neuropathic disorder is an intensely stressful to bear for patient and impacts the quality of life. Most of the cases of TN arise when the root of fifth cranial nerve, i.e., trigeminal nerve is compressed after a few millimeters of its entry into the pons. This article describes various animal models and the role of biomarkers to study the underlying mechanisms of neuropathic pain in animal models as well as different modes of management of TN.






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