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Year : 2022  |  Volume : 54  |  Issue : 1  |  Page : 58-62

Aging, VO2 max, entropy, and COVID-19


1 Spedding Research Solutions SAS, 6 Rue Ampère, 78110 Le Vésinet, France
2 IRMES (Institut de Recherche bioMédicale et d'Épidémiologie du Sport), INSEP (Institut national du sport, de l'expertise et de la performance), 11, avenue du Tremblay, 75012 Paris, France
3 IRMES (Institut de Recherche bioMédicale et d'Épidémiologie du Sport), INSEP (Institut national du sport, de l'expertise et de la performance), 11, avenue du Tremblay, 75012 Paris; Institut de Mathématiques de Bourgogne, UMR 5584 CNRS, Université Bourgogne Franche-Comté, Faculté des Sciences Mirande, 9 avenue Alain Savary, 21000 Dijon; Scientific Department, French Ski Federation, 50 rue des marquisats, 74000 Annecy, France
4 IRMES (Institut de Recherche bioMédicale et d'Épidémiologie du Sport), INSEP (Institut national du sport, de l'expertise et de la performance), 11, avenue du Tremblay, 75012 Paris; EA7329, Université de Paris, 12, rue de l'École de Médecine, 75006 Paris; CIMS, Hôtel-Dieu, Assistance Publique - Hôpitaux de Paris, Parvis-Notre-Dame, 75004 Paris, France

Correspondence Address:
Prof. Michael Spedding
Spedding Research Solutions SAS, 6 Rue Ampère, 78110 Le Vésinet
France
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijp.ijp_442_21

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The decline in human performance with age at 5000 m, an athletic event requiring high VO2 max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows the limitations for therapy of aging. Mortality incidence for COVID-19 shows a similar relationship. We propose that initial VO2 max has a critical role in COVID sensitivity because of the direct relationship of disease severity with oxygen use, and the parallel decline in aging.






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