DRUG WATCH |
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Year : 2019 | Volume
: 51
| Issue : 4 | Page : 279-281 |
A pediatric case report of fixed drug eruption related to carmoisine colorant present in paracetamol syrup
George Mathew Panachiyil1, Tirin Babu1, Juny Sebastian1, Narayanappa Doddaiah2
1 Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysore, Karnataka, India 2 Department of Pediatrics, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysore, Karnataka, India
Correspondence Address:
Dr. Juny Sebastian Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysore - 570 015, Karnataka India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijp.IJP_29_19
Various adverse drug reactions, including hypersensitivity skin reaction after the exposure to carmoisine colorant, have already been reported in the literature. This case report gives the details of a 5-year-old male child with a recurrent fixed drug eruption (FDE) over the neck and trunk after the use of paracetamol syrup containing carmoisine as a colorant. Patch test to the carmoisine colorant in the paracetamol syrup was positive. This case report adds an increased awareness of the probability of allergic skin reaction to carmoisine in a previously sensitized person. The report also emphasizes the necessity to consider artificial dyes in pharmaceutical products as a potential cause for FDE.
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