| DRUG WATCH |
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| Year : 2019 | Volume
: 51
| Issue : 2 | Page : 120-122 |
Phenytoin-induced bradycardia and hypotension
Swetha Reba Mathews1, Dinesh Kumar Badyal1, Renji Mathew2
1 Department of Pharmacology, Christian Medical College and Hospital, Ludhiana, Punjab, India
2 Department of Surgery, Christian Medical College and Hospital, Ludhiana, Punjab, India
Correspondence Address:
Dr. Dinesh Kumar Badyal
Department of Pharmacology, Christian Medical College and Hospital, Ludhiana - 141 008, Punjab
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijp.IJP_254_17
Phenytoin is an anticonvulsant which is also a Class IB antiarrhythmic. Its common adverse drug reactions (ADRs) include gastrointestinal symptoms, psychiatric disorders, gingival hyperplasia, and rash. Bradycardia and hypotension following intravenous (IV) phenytoin are rare ADRs. We report the case of a 62-year-old female with subarachnoid hemorrhage and right bundle branch block, who developed sinus bradycardia and hypotension on administration of IV phenytoin. This case report serves as a note for caution on patient selection for the administration of phenytoin and highlights the need for specific guidelines on the same.
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