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 DRUG WATCH
Year : 2018  |  Volume : 50  |  Issue : 4  |  Page : 212-214

Zidovudine-induced lactic acidosis with acute pancreatitis and myopathy: Lethal and rare complications


Department of Medicine, PGIMER, Dr. RML Hospital, New Delhi, India

Correspondence Address:
Dr. Subodh Kumar Mahto
Department of Medicine, OPD Block, PGIMER, Dr. RML Hospital, New Delhi - 110 001
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijp.IJP_285_18

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Highly active antiretroviral therapy (HAART) is nowadays universally available to patients with HIV/AIDS. This has led to increased longevity in people living with HIV/AIDS. However, these patients frequently face chronic and rarely acute life-threatening complications of HAART. Herein, we report the case of a patient who was on HAART and developed zidovudine-induced lactic acidosis, acute pancreatitis, and myopathy. Although these acute complications are rare, a high index of suspicion is required for early diagnosis and to reduce significant morbidity and mortality.






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