| DRUG WATCH |
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| Year : 2015 | Volume
: 47
| Issue : 2 | Page : 227-229 |
A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
Mahesh N Belhekar1, Sarayu Pai1, Parimal Tayade2, Pradip Dalwadi2, Renuka Munshi1, Prema Varthakavi2
1 Department of Clinical Pharmacology, T. N. Medical College and B. Y. L. Nair Charitable Hospital, Mumbai, Maharashtra, India
2 Department of Endocrinology, T. N. Medical College and B. Y. L. Nair Charitable Hospital, Mumbai, Maharashtra, India
Correspondence Address:
Renuka Munshi
Department of Clinical Pharmacology, T. N. Medical College and B. Y. L. Nair Charitable Hospital, Mumbai, Maharashtra
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.153438
Insulin is an important agent for the treatment of diabetes mellitus (DM). Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. Hypersensitivity to insulin has considerably been reduced with the introduction of human insulin produced by recombinant deoxyribonucleic acid technology. Here, we present a case of Type 2 DM who demonstrated immediate (Type 1) hypersensitivity reaction on the sites of subcutaneous injection of soluble and isophane insulin but insulin glargine was tolerated well and provided good glycemic control.
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