DRUG WATCH |
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Year : 2014 | Volume
: 46
| Issue : 5 | Page : 555-556 |
Gastrointestinal bleed induced by a fixed dose combination of rabeprazole and diclofenac sodium
Vishal R Tandon1, Vijant Chandail2, Vijay Khajuria1, Zahid Gillani1
1 Postgraduate Departments of Pharmacology and Therapeutic, Government Medical College, Jammu and Kashmir, India 2 Medicine (Gastroenterology), Government Medical College, Jammu and Kashmir, India
Correspondence Address:
Vishal R Tandon Postgraduate Departments of Pharmacology and Therapeutic, Government Medical College, Jammu and Kashmir India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.140597
Non-steroidal anti-inflammatory drugs (NSAIDs) are known to cause gastrointestinal (GI) bleed. Co-administration of proton pump inhibitors (PPIs) has been widely suggested as one of the strategies to prevent these GI complications among NSAIDs users. Herein, we present a case of severe GI bleeding in a patient taking fixed dose combination (FDC) of rabeprazole (20 mg) and diclofenac sodium (100 SR).
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