| DRUG WATCH |
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| Year : 2014 | Volume
: 46
| Issue : 3 | Page : 343-344 |
Acute hepatic injury with atorvastatin: An unusual occurrence
Pinki Vishwakarma1, Rajiv Nehra2, Alok Kumar3
1 Department of Pharmacology, LLRM Medical College, Meerut, Uttar Pradesh, India
2 Department of Biochemistry, LLRM Medical College, Meerut, Uttar Pradesh, India
3 Forensic Medicine and Toxicology, RIMS and R, Saifai, Etawah, Uttar Pradesh, India
Correspondence Address:
Pinki Vishwakarma
Department of Pharmacology, LLRM Medical College, Meerut, Uttar Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.132197
Atorvastatin, a commonly used and well-tolerated hypolipidemic drug, belongs to the class of statins or hydroxymethylglutaryl-coenzyme A reductase inhibitors. Use of atorvastatin may be associated with minor asymptomatic elevations in serum aminotransferases, but clinically significant hepatotoxicity is usually infrequent. Here we present a case of self-limiting clinically apparent acute hepatic injury attributable to atorvastatin occurring at recommended daily dose of 20 mg once a day. This case was postulated to be an unusual idiosyncratic reaction of the drug.
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