| SHORT COMMUNICATION
|Year : 2013 | Volume
| Issue : 2 | Page : 180-183
Comparison of the pattern, efficacy, and tolerability of self-medicated drugs in primary dysmenorrhea: A questionnaire based survey
Ramya Sugumar1, Vasundara Krishnaiah1, Gokul Shetty Channaveera2, Shilpa Mruthyunjaya3
1 Department of Pharmacology, Kempegowda Institute of Medical Sciences, Bangalore, Karnataka, India
2 Department of Pharmacology, Jagadguru Jayadeva Murugarajendra Medical College, Davangere, Karnataka, India
3 Department of Physiology, Mysore Medical College, Mysore, Karnataka, India
Objective: To compare the pattern, efficacy, and tolerability of self-medicated drugs and to assess the adequacy of their dose in primary dysmenorrhea (PD).
Materials and Methods: A survey using a self-developed, validated, objective, and structured questionnaire as a tool was conducted among subjects with PD. Statistical analysis was carried out using Chi-square test and ANOVA with post-hoc Tuckey's test.
Results: Out of 641 respondents, 42% were self-medicated. The pattern of drugs used was: Dicyclomine, an unknown drug, mefenamic acid, mefenamic acid + dicyclomine, and metamizole by 35%, 29%, 26%, 9%, and 1% of respondents, respectively. Mefenamic acid + dicyclomine, the combination was the most efficacious in comparison to other drugs in moderate to severe dysmenorrhea. There was better tolerability with mefenamic acid + dicyclomine group compared to other drugs. Sub-therapeutic doses were used by 86% of self-medicating respondents.
Conclusions: The prevailing self-medication practices were inappropriate in a substantial proportion of women with inadequate knowledge regarding appropriate drug choice, therapeutic doses, and their associated side effects.
Department of Pharmacology, Kempegowda Institute of Medical Sciences, Bangalore, Karnataka
Source of Support: None, Conflict of Interest: None
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