| RESEARCH ARTICLE
|Year : 2013 | Volume
| Issue : 1 | Page : 66-70
Experimental evaluation of analgesic and anti-inflammatory potential of Oyster mushroom Pleurotus florida
Aditya Ganeshpurkar1, Gopal Rai2
1 Department of Pharmacy, Shri Ram Institute of Technology, Jabalpur, Madhya Pradesh, India
2 Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh, India
Background: Edible mushrooms have been used as flavorful foods and as health nutritional supplements for several centuries. A number of bioactive molecules have been identified in numerous mushroom species
Objective: To evaluate the analgesic and anti-inflammatory potential of Oyster Mushroom Pleurotus florida using various experimental models in Wistar rats.
Materials and Methods: Acute toxicity studies were performed whereby dose of 250 mg/ kg and 500 mg/kg was selected for present study, Analgesic activity was determined using hot plate method, tail flick method, acetic acid induced writhing and formalin induced pain in rats, while carrageenan was used to induce inflammation and anti-inflammatory studies were performed.
Results: HEE showed significant (P < 0.01) analgesic and anti-inflammatory response against all experimental models.
Conclusion: These studies conclude that Pleurotus florida possesses analgesic and anti- inflammatory potential which might be due to presence of myochemicals like flavonoids, phenolics and polysaccharides.
Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh
Source of Support: None, Conflict of Interest: None
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