IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1342 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2587    
    Printed114    
    Emailed0    
    PDF Downloaded185    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 

 SHORT COMMUNICATION
Year : 2012  |  Volume : 44  |  Issue : 6  |  Page : 788-791

Evaluation of anti-inflammatory activity of Typha angustifolia pollen grains extracts in experimental animals


1 Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai, India
2 Department of Physiology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai Central, Mumbai, India
3 Department of Physiology, K. J. Somaiya Medical College, Sion, Mumbai, India

Correspondence Address:
Archana R Juvekar
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai
India
Login to access the Email id

Source of Support: UGC, Conflict of Interest: None


DOI: 10.4103/0253-7613.103303

Rights and Permissions

Objective: This study was designed to evaluate the anti-inflammatory activity of aqueous and 70% methanolic extracts of pollen grains of Typha angustifolia. Materials and Methods: Female Sprague Dawley rats were used for the study. The acute anti-inflammatory activity of pollen grains of T. angustifolia was studied using the carrageenan as phlogistic agent, whereas its chronic anti-inflammatory effect was investigated by the percentage inhibition of cotton pellet-induced granuloma. Results: Both aqueous and 70% methanolic extracts of pollen grains of T. angustifolia showed significant dose-dependent inhibition of carrageenan-induced paw edema as compared to the control (P<0.001). It was observed that both the extracts at dose of 125 mg/kg inhibited the granuloma formation by 44.30% which is higher than at dose of 500, 250 mg/kg, thus causing a significant (P<0.001) non-dose-related inhibition of granuloma formation. Conclusion: The results of this study indicate that extracts of pollen grains of T. angustifolia are effective in the treatment of both acute and chronic inflammatory conditions and thus support its traditional utilization.






[FULL TEXT] [PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow