| DRUG WATCH |
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| Year : 2012 | Volume
: 44
| Issue : 3 | Page : 415-416 |
Norfloxacin-induced hypoglycemia and urticaria
Ajay Mishra, Nikhil Dave
Department of Medicine, Pramukhswami Medical College, Karamsad, India
Correspondence Address:
Ajay Mishra
Department of Medicine, Pramukhswami Medical College, Karamsad
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.96352
Fluoroquinolone-induced hypoglycemia is not a common adverse drug reaction. However, it has been reported with most of the available agents and appears to be more common in elderly patients with a history of type 2 diabetes who are receiving oral sulfonylureas. The exact mechanism of this effect is unknown but is postulated to be a result of blockage of Adenosine 5'-Triphosphate (ATP)-sensitive potassium channels in pancreatic β-cell membranes. This report highlights hypoglycemia with urticaria as an adverse drug reaction of norfloxacin in a middle aged non-diabetic patient. Clinicians should be alert about the possibility of its potential adverse effect in patients who are receiving norfloxacin therapy.
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