IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 2660 
Small font sizeDefault font sizeIncrease font size
Navigate Here
  Search
 
  
Resource Links
   Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
   Article in PDF (213 KB)
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)

 
In This Article
   References

 Article Access Statistics
    Viewed1127    
    Printed51    
    Emailed0    
    PDF Downloaded89    
    Comments [Add]    

Recommend this journal

 


 
 Table of Contents    
LETTER TO THE EDITOR
Year : 2012  |  Volume : 44  |  Issue : 1  |  Page : 140-141
 

Authors' reply


1 Department of Pharmacology, Government Medical College, Nagpur, Maharashtra, India
2 Department of Pharmacology, VCSG GMSRI, Srinagar, Pauri Garhwal, Uttarakhand, India

Date of Web Publication14-Jan-2012

Correspondence Address:
Vijay Thawani
Department of Pharmacology, VCSG GMSRI, Srinagar, Pauri Garhwal, Uttarakhand
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions



How to cite this article:
Bajait C, Thawani V. Authors' reply. Indian J Pharmacol 2012;44:140-1

How to cite this URL:
Bajait C, Thawani V. Authors' reply. Indian J Pharmacol [serial online] 2012 [cited 2021 Sep 28];44:140-1. Available from: https://www.ijp-online.com/text.asp?2012/44/1/140/91892


Sir,

The mechanism of action of zinc to inhibit ion transport as mentioned by you [1] is based on the report published in Jan 2011. [2] This was after our paper was sent for publication. [3] However, the facts mentioned in our paper are based on the literature available that time. We accept the new findings mentioned by you that are supported by the new published literature.

Regarding the efficacy of zinc based on the etiological factor, we would like to clarify that we did not take into consideration the etiological factors but discussed in general the beneficial effects of zinc in diarrhea. Even otherwise clinically it is not always possible to establish the causative organism and treatment cannot be withheld till reports of laboratory investigations are available. Further, WHO has recommended that zinc supplements should be administered in diarrhea from the day of onset of symptoms along with ORS. [4]

We agree to the probable reasons proposed by you as far as the differential effects of zinc in diarrhea are concerned as no published study has investigated the efficacy of zinc in zinc-deficient state.

 
  References Top

1.Das RR. Zinc in acute childhood diarrhea: Is it universally effective? Indian J Pharmacol 2012;44:140.  Back to cited text no. 1
  Medknow Journal  
2.Berni Canani R, Buccigrossi V, Passariello A. Mechanisms of action of zinc in acute diarrhea. Curr Opin Gastroenterol 2011;27:8-12.  Back to cited text no. 2
    
3.Bajait C, Thawani V. Role of zinc in pediatric diarrhea. Indian J Pharmacol 2011;43:232-5.  Back to cited text no. 3
[PUBMED]  Medknow Journal  
4.WHO/UNICEF Joint Statement-Clinical management of acute diarrhoea. (WHO/FCH/CAH/04.07). Geneva and New York: World Health Organization and United Nations Children's Fund; 2004.  Back to cited text no. 4
    




 

Top
Print this article  Email this article
 

    

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow