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Year : 2011  |  Volume : 43  |  Issue : 2  |  Page : 214-215

Chronic phenytoin therapy-induced vecuronium resistance


1 Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, India
2 Department of Anesthesiology, R.G. Kar Medical College & Hospital, Kolkata, India
3 Department of Surgery, R.G. Kar Medical College & Hospital, Kolkata, India

Correspondence Address:
Lopamudra Chowdhury
Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.77378

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This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.






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