| DRUG WATCH |
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| Year : 2011 | Volume
: 43
| Issue : 2 | Page : 214-215 |
Chronic phenytoin therapy-induced vecuronium resistance
Lopamudra Chowdhury1, Arpita Laha2, Tamonash Chaudhuri3, Suparna Chatterjee1
1 Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata, India
2 Department of Anesthesiology, R.G. Kar Medical College & Hospital, Kolkata, India
3 Department of Surgery, R.G. Kar Medical College & Hospital, Kolkata, India
Correspondence Address:
Lopamudra Chowdhury
Department of Pharmacology, Institute of Postgraduate Medical Education & Research, Kolkata
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.77378
This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.
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