| EDUCATIONAL FORUM |
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| Year : 2010 | Volume
: 42
| Issue : 6 | Page : 334-337 |
Role of coenzyme Q 10 as an antioxidant and bioenergizer in periodontal diseases
Shobha Prakash, J Sunitha, Mayank Hans
Department of Periodontics, College of Dental Sciences, Davangere, Karnataka, India
Correspondence Address:
Shobha Prakash
Department of Periodontics, College of Dental Sciences, Davangere, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.71884
Periodontal disease is an inflammatory disease process resulting from the interaction of a bacterial attack and host inflammatory response. Arrays of molecules are considered to mediate the inflammatory response at one time or another, among these are free radicals and reactive oxygen species (ROS). Periodontal pathogens can induce ROS overproduction and thus may cause collagen and periodontal cell breakdown. When ROS are scavenged by antioxidants, there can be a reduction of collagen degradation. Ubiquinol (reduced form coenzyme Q 10 ) serves as an endogenous antioxidant which increases the concentration of CoQ 10 in the diseased gingiva and effectively suppresses advanced periodontal inflammation.
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