| DRUG WATCH |
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| Year : 2010 | Volume
: 42
| Issue : 5 | Page : 318-319 |
Flucytosine for treatment of Candida albicans in H1N1-positive patient
Tanvir Samra, Amlendu Yadav, Neerja Banerjee, Mridula Pawar, Desh Deepak
Department of Anaesthesia and Intensive Care, Dr Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, Connaught Place, New Delhi - 110 001, India
Correspondence Address:
Tanvir Samra
Department of Anaesthesia and Intensive Care, Dr Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, Connaught Place, New Delhi - 110 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.70398
A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida species sensitive to flucytosine but resistant to amphotericin B and azole group of antifungals. Monotherapy with flucytosine led to clinical and radiological improvement.
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