| SHORT COMMUNICATION
|Year : 2002 | Volume
| Issue : 4 | Page : 264-268
Effect of sparfloxacin and terfenadine combination on QT-intervals at various RR-intervals
Akhtar Mohd, N Saha, A Roy, KK Pillai
Extracts of Artemisia japonica, Artemisia maritima. Artemisia nilegarica in ethanol and light petroleum were tested for antimalarial activity.In vivo studies were carried out in mice using the Rane test. All the compounds prolonged survival time of mice as compared to control mice in the dose range of 640-320 mg/kg subcutaneusly. Chloroquine sensitive (FDL-Rl) strain of Plasmodium falciparum was used for in vitro studies. All the three compounds inhibited schizont maturation in concentration dependent manner in the range of 2.5 (g to 40 (g per 10 (g blood.
Source of Support: None, Conflict of Interest: None