| REVIEW ARTICLE |
|
| Year : 2000 | Volume
: 32
| Issue : 2 | Page : 94-101 |
Antidotes to cyanide poisoning: present status
R Bhattacharya
Correspondence Address:
R Bhattacharya
 Source of Support: None, Conflict of Interest: None  | Check |
Cyanide is ubiquitously present in the environment. It is considered as a potent suicidal, homicidal, genocidal and chemical warfare agent. Cyanide toxicity is mediated through inhibition of cellular respiration, but its other complex toxic manifestations are also well documented. There are a number of antidotes available for cyanide poisoning ( e.g. sodium nitrite, 4-dimethyl aminophenol, sodium thiosulphate, etc.), however, there is still uncertainty about their safety, efficacy and correct indication for use. This review provides a comprehensive account of toxicology of cyanide and the present status of various antidotes employed clinically or pursued experimentally.
[PDF]*
|
