SHORT COMMUNICATION |
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Year : 1999 | Volume
: 31
| Issue : 3 | Page : 229-231 |
Effect of gentamicin on specific immune response in rabbits
HB Asha, gowda Honne, K Narayana, G Krishnappa, K Jayakumar
Correspondence Address:
H B Asha
 Source of Support: None, Conflict of Interest: None  | Check |

Objective: To study the effect of gentamicin on humoral and cell mediated immune system in rabbits.
Methods: Rabbits were treated with gentamicin at 4 mg/kg and 8mg/kg body weight doses for 5 days along with single intramuscular injection of 0.5 ml of Brucella plain killed antigen and humoral and cellular immune responses were measured.
Results: There was no significant variation in the humoral and cellular immune response between the antigen control and the groups given gentamicin along with antigen.
Conclusion: Gentamicin at the two dose levels used for 5 days, in rabbits, did not affect the specific immune response.
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