| RESEARCH PAPER |
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| Year : 1999 | Volume
: 31
| Issue : 2 | Page : 124-127 |
The effect of panax ginseng and diazepam on norepinephrine levels of whole brain and hypothalamus during stress
D Bhattacharyya, TK Sur
Correspondence Address:
D Bhattacharyya
 Source of Support: None, Conflict of Interest: None  | Check |
Objective: To see the effect of anti-stress agents like Panax ginseng and diazepam on stress-induced elevation of norepinephrine (NE) in brain and hypothalamus of rats.
Methods: NE was estimated in brain and hypothalamus of rats by spectrophotofluorimetry. Plasma corticosterone was measured by fluorimetry.
Results: Panax ginseng and diazepam both per se did not modify NE levels of brain and hypothalamus in unstressed rats. But both the drugs attenuated stress-induced elevation of NE of brain and hypothalamus and simultaneously attenuated stress-induced elevation of plasma corticosterone.
Conclusion: Anti-stress effect of Panax ginseng and diazepam seems to be mediated through attenuation of levels of NE in brain and hypothalamus.
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