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Year : 1998  |  Volume : 30  |  Issue : 4  |  Page : 209-217

Treatment of arsenic poisoning: An update



Correspondence Address:
SJS Flora


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Source of Support: None, Conflict of Interest: None


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Arsenic, a metalloid of highly toxic nature is present throughout the earth's crust. In India about 40 lakhs of people in West Bengal suffer from arsenic poisoning due to drinking water contamination. British Anti lewisite (BAL) is used for the treatment of arsenic poisoning. However, the chelator has low safety ratio and unpleasant side effects. Recently, few analogues of BAL, viz., meso 2,3-dimercaptosuccinic acid (DMSA) and sodium 2,3-dimercaptopropane 1 sulfonate (DMPS) beside few diesters and monoesters of DMSA have been successfully tried both in humans as well as in experimental models of acute and chronic arsenic poisoning. This article presents in briefly the recent development made in this area with possible directions for future research.






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