IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 3166 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 ╗   Next article
 ╗   Previous article
 ╗   Table of Contents

Resource Links
 ╗   Similar in PUBMED
 ╗  Search Pubmed for
 ╗  Search in Google Scholar for
 ╗Related articles
 ╗   Citation Manager
 ╗   Access Statistics
 ╗   Reader Comments
 ╗   Email Alert *
 ╗   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded121    
    Comments [Add]    

Recommend this journal


Year : 1996  |  Volume : 28  |  Issue : 3  |  Page : 181-184

Evaluation of clinical efficacy and safety of hydroxyethyl starch

Correspondence Address:
Rani P Usha

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Hydroxyethyl starch (HES) 6% has been shown to improve hypovolaemia, with minimum side effects and long duration of action. Thirty patients showing signs of hypovolaemia post-operatively, in the form of tachycardia and hypotension received 500 ml of 6% HES intravenously over 30-60 minutes. Administration of HES, significantly improved hypovolaemia in all the patients. Within 30 minutes after infusion, systolic blood pressure (SBP) increased from 85˝ 6 to 98˝ 8 mm Hg. Heart rate decreased from 124˝ 3 beats per minute (bpm) to 99˝ 6 bpm and central venous pressure (CVP) increased from 1˝ 1 to 3.5k1.2 cm of saline, at one hour post HES administration. This improvement persisted till the end of sixth hour observation period. All patients tolerated HES well without any side effects and hematological or biochemical abnormalities.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow