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Year : 1996  |  Volume : 28  |  Issue : 3  |  Page : 171-174

Hypocholesterolemic effect of turmeric extract on Swiss mice

Correspondence Address:
P B Godkar

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Source of Support: None, Conflict of Interest: None

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Hypercholesterolemia was developed in mice fed with hypercholesterolemic diet (HC) made of 1 g cholesterol, 0.2 g cholic acid and 98.8 g standard diet. Mice were fed HC diet for 15, 30, 45 and 60 days, and serum and liver cholesterol, triglycerides (TG) and total lipids (TL) were measured. Cholesterol level increased substantially at 15 days in serum and liver. It increased further at later time points upto 8 weeks. Treatment of 5% turmeric extract (TE) mixed with standard diet to hypercholesterolemic mice significantly decreased serum and hepatic cholesterol, triglycerides (TG) and total lipids (TL) levels. Feeding with 10% TE diet brought the levels comparable to those in normal untreated mice.


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