IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1645 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded137    
    Comments [Add]    

Recommend this journal


Year : 1996  |  Volume : 28  |  Issue : 2  |  Page : 93-97

Glutathione and glutathione redox cycle in riboflavin supplemented cataractous rat lenses

Correspondence Address:
R R Vani

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Effect of riboflavin supplementation on glutathione and glutathione redox cycle in selenite induced cataractous rat lenses was studied, as the lens negates some of the toxic effects of the oxidants by its glutathione mediated defence mechanisms. The alterations in the level of proteins, reduced glutathione (GSH) and the activity of (-glutamylcysteine synthetase ((-GCS), glutathione reductase (GR) and glutathione peroxidase (GSH-Px) have been studied in the control and riboflavin supplemented rats. The cataractous littermates supplemented with riboflavin showed increased activity of the enzymes and elevated levels of metabolites as compared to the cataractous, non-supplemented littermates. The results of this study point towards the role of riboflavin in the prevention of cataract, induced by selenite.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow