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Year : 1996  |  Volume : 28  |  Issue : 2  |  Page : 116-119

Anti-arthritic and anti-inflammatory effect of a poly-herbal drug (EASE)@: Its mechanism of action

Correspondence Address:
S Chatterjee

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Source of Support: None, Conflict of Interest: None

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Anti-arthritic and anti-inflammatory action of a poly-herbal formulation (Ease(r)) was compared with standard anti-inflammatory drugs in different in vivo and in vitro test models. Treatment with Ease(r) significantly reduced adjuvant-induced non- established and established arthritis in rats and the effect was comparable to phenylbutazone. It also provided significant protection against protein denaturation and RBC membrane damage in the in vitro models, Results were comparable to acetyl salicylic acid. Ease(r) also exhibited significant proteinase inhibitory action. It is concluded that Ease(r) may prove to be a useful anti-arthritic product in future.


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