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Year : 1995  |  Volume : 27  |  Issue : 4  |  Page : 262-264

Antidiarrhoeal evaluation of Nelumbo nucifera rhizome extract

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A study was undertaken to evaluate the effects of methanolic extract of rhizomes of Nelumbo nucifera Gaertn (FINN) for its antidiarrhoeal potential against several experimental models of diarrhoea in rats. RNN treated animals showed significant inhibitory activity against castor oil induced diarrhoea and inhibited significantly PGE, induced enteropooling in rats. It also showed significant reduction in gastrointestinal motility following charcoal meal in rats. The results obtained establish the efficacy of RNN as an antidiarrhoeal agent.


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