IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 4147 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded203    
    Comments [Add]    
    Cited by others 5    

Recommend this journal


Year : 1995  |  Volume : 27  |  Issue : 4  |  Page : 214-221

Neurosteroids: novel regulators of neural functions

Correspondence Address:
M R Jain

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Recent studies have demonstrated that some of the enzymes involved in the biosynthesis of steroidal hormones are found in a cell specific and region specific fashion in the brain. The discovery of the biosynthesis of steroids in the brain has generated considerable ex citement. These brain derived steroids (named 'neurosteroids'), in addition to binding to the cytoplasmic/nuclear receptors also interact with the specific binding sites on the GABAA receptor. Several biological functions have been proposed for these neurosteroids for their roles in hypnosis, anxiety, analgesia, convulsion, neural development and regulation of endocrine systems, Although in its infancy, the study of the neurosteroids is an emerging line that has shown considerable potential. It is hoped that the work on neurosteroids in addition to throwing new light on the neural processes, may provide a substratum for the development of new drugs for several neural disorders.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow