IPSIndian Journal of Pharmacology
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 RESEARCH PAPER
Year : 1995  |  Volume : 27  |  Issue : 3  |  Page : 167-170

Effect of nifedipine and aspirin on platelet aggregation: A study in hypertensive patients and normal volunteers



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A A Desai


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We studied the pattern of platelet aggregation in normal subjects as well as in patients of essential hypertension. Our study revealed that platelet aggregation was enhanced in hy-pertensive patients as compared to normal healthy volunteers. Both nifedipine (10 mg) and aspirin (75 mg) inhibited the platelet aggregation when administered alone or in combination both in hypertensive patients and in normal subjects. The combination of these two drugs might be of importance in routine use for essential hypertension for the combined effect of controlling the hypertension by nifedipine and inhibiting platelet aggregation by both nifedipine and aspirin.






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