| SHORT COMMUNICATION |
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| Year : 1994 | Volume
: 26
| Issue : 4 | Page : 304-306 |
Lack of genotoxicity of omeprazole in chromosomal aberration and sisterChromatid exchange assays using cultured human lymphocytes in vitro
TS Kumaravel, Lakshmi Karthika, P Balakrishnamurthy
Correspondence Address:
T S Kumaravel
 Source of Support: None, Conflict of Interest: None  | Check |
Omeprazole was tested in chromosomal aberration (CA) and sister chromatid exchange (SCE) assays using cultured human lymphocytes in vitro. While CA is a standard battery of test system in mutagenicity studies, SCE is considered to be the most simple reliable and sensitive index of DNA damage/repair. Omeprazole was found to be non toxic in both these tests.
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